The 49ers will be on the road for the second week in a row, visiting the Rams in an NFC West matchup for Week 3.
The Niners are coming off a 23-17 loss to the Vikings, a performance that just didn't look up to standard for San Francisco in a deafening US Bank Stadium on Sunday. With star running back Christian McCaffrey now on the Injured Reserve, the squad struggled to convert on several drives.
Even while scoring on two takeaways forced by All-Pro linebacker Fred Warner, San Francisco ultimately made too many mistakes, giving up a blocked punt, two true turnovers and a 97-yard touchdown to Justin Jefferson.
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After a tough overtime loss to the Lions in Week 1, the Rams in Week 2 were blown out by the Cardinals, 41-10. Despite beating Arizona 13 out of the last 15 times they've met, Los Angeles truly had no answer for Kyler Murray or James Conner this time around.
Wide receiver Cooper Kupp leaving mid-game with an ankle injury was no help to the cause. The Rams have now fallen to 0-2 and the bottom of the NFC West.
Who will come back with a win this week? Here's everything you need to know about the 49ers vs. Rams matchup.
What channel is 49ers vs. Rams on today?
49ers vs. Rams will be broadcast nationally on Fox.
Fans can also stream this game on Fubo, which offers a free trial for all new customers.
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NFL Week 2 schedule 2024
Thursday, Sept. 19
| Game | Time (ET) | TV Channel |
| Patriots vs. Jets | 8:15 p.m. | FOX |
Sunday, Sept. 22
| Game | Time (ET) | TV channel |
|---|---|---|
| Giants vs. Browns | 1 p.m. | FOX |
| Eagles vs. Saints | 1 p.m. | FOX |
| Texans vs. Vikings | 1 p.m. | CBS |
| Broncos vs. Buccaneers | 1 p.m. | FOX |
| Packers vs. Titans | 1 p.m. | FOX |
| Bears vs. Colts | 1 p.m. | CBS |
| Chargers vs. Steelers | 1 p.m. | CBS |
| Dolphins vs. Seahawks | 4:05 p.m. | CBS |
| Panthers vs. Raiders | 4:05 p.m. | CBS |
| 49ers vs. Rams | 4:25 p.m. | FOX |
| Lions vs. Cardinals | 4:25 p.m. | FOX |
| Ravens vs. Cowboys | 4:25 p.m. | FOX |
| Chiefs vs. Falcons | 8:20 p.m. | NBC |
Monday, Sept. 23
| Game | Time (ET) | TV channel |
|---|---|---|
| Jaguars vs. Bills | 7:30 p.m. | ESPN |
| Commanders vs. Bengals | 8:15 p.m. | ABC |